Original Research Article
ABSTRACT
The study aimed to determine the work environment, challenges, and teaching performance of the newly hired teachers in the new normal of Zone 2, Schools Division of Zambales. The study used a quantitative descriptive research design in its presentation. A survey-questionnaire was the main instrument of data gathering for the study. A total of one hundred (100) newly hired teachers served as the respondents of the study. Frequency, percentage, weighted mean, Analysis of Variance, and Pearson Product- Moment Correlation was employed in the data analysis and interpretation. The findings of the study revealed that teaching performance of the newly hired teachers is affected by the kind of work environment in terms of Facilities & Equipment, School Typology, Physical Environment, Alternative Work from Home and Administrative/ Supervisor’s Support. Furthermore, the newly hired teachers strongly agreed that addressing the challenges in the workplace as to fitting in, time management and productivity, culture in the workplace, communication and coordination and motivation will increase their teaching performance. It was noted that there was no significant relationship between the teaching performance based on the IPCRF and work environment and on addressing the challenges of the newly hired teachers.
Original Research Article
ABSTRACT
Background: The enlargement of prostate is known as benign prostatic hypertrophy (BPH). It begins when the cells of the prostate gland begin to proliferate. BPH is caused by increased age and other factors associated with it. Objective: To determine the correlation of prostate volume with age and post-micturating residual (PMR) volume in patients with benign prostatic hyperplasia (BPH). Methods: This cross-sectional study was conducted on 100 patients of BPH that fulfilling inclusion criteria for 4 months, selected from Gondal Medical Complex Gujranwala during 14 January to 15 May 2022. Patients with prostate cancer, mild urinary tract or prostate surgery, and those with UTI or stone in bladder were excluded. Ultrasound was used to perform a transabdominal scan. Age, prostate volume (PV), and PMRV were the outcome parameters. Results: In this study hundred BPH positive patients were included. The mean age of patients with BPH, prostate weight, post-void residual volume of the participants was found to be 64.89±14.12 years, 54.68±29.42g, and 22.47±14.75ml respectively. In this study the correlation value of age of patients with BPH and prostate volume was 0.212 and P-value was 0.035 which was significant but the correlation between PV and PMRV was not significant because the correlation value of PV and PMRV was 0.032 and P-value was 0.751. Conclusion: This study concluded that there was significant correlation between Age and BPH but no significant correlation between BPH and PMRV.
Original Research Article
ABSTRACT
Background: Head injuries constitute a real public health problem in Low Income Countries. The aim of this study is to evaluate the management of severe head trauma. Patients and methods: A prospective study was conducted for a period of six months, from 1st February to 31th July 2018 at Niamey National Hospital. Were been Included all patients victims of head injury with Glasgow Coma Scale (GCS) less than 8. The following variables were studied: age, sex, cause of trauma, deadline admission, means of transport used, Glasgow Coma Scale, CT Scan results, management and evolution. Results: Out of 1,918 patients admitted; 243 were head trauma, of which 76 patients had a GCS less than 8 (3.96%). Male predominance was found with a sex ratio of 24.33, young people was the most concerned (mean age:29.88 ± 16.37 years). Predominant age group was 16 to 30 years old, with 43.42% of patients. The circumstances of the trauma were road traffic accidents (86.84%). Transportation was medicalized in 15%. GCS was between 6 to 8 in 74.02% and the admission deadline was less than 6 hours in 77.63%. Respiratory distress was found in 28.95% and circulatory distress in 14.47%. Cranio-cerebral CT scan was performed in 82.89%. Seven patients (9.21%) were intubated and ventilated. Death rate was 53.94%. Conclusion: Head injury concerns a young male patient, the cause was a road traffic accident, this situation could be improved by raising the population's awareness of road safety and greater efficiency in taking in medical charge.
ABSTRACT
All the material presented in this thesis as well as the author’s implications/conclusions prove that a living organism can be perceived as a complex electronic device similar to technical devices, whereas biological materials (proteins, DNA, RNA) - as components of electronic devices. These arguments allow us to state that a biological system can be considered to be a quantum computer that functions on the basis of entangled quantum states and optoelectronic phenomena. Melanin and neuromelanin are involved in the central control of all biological, physiological and psychological processes. Numerous modular communication systems and signalling pathways that transmit signals into cells are generated under the influence of light. Melanin and neuromelanin function as multireceptors of a full range of electromagnetic, acoustic, and soliton waves, torsion fields and bioplasma, which does not receive so much information as the senses do, but receive it constantly. The role of photoreceptors, receptors of hearing and touch is limited to a single reception of a stimulus, whereas melanin and neuromelanin play an integrative function, combining stimulus elements into a whole, namely combining movement with space and time, sound with light, space and time. From the psychological point of view, melanin and neuromelanin are responsible for the entire process of adaptation to the environment, mental development, the development of attention and perceptual experience, which, together with an increase in melanin and neuromelanin, acquire better sharpness and quality. Bioplasma controls these processes.
Original Research Article
ABSTRACT
Background: Pancreatic calculi are a condition characterised by irreversible destruction and fibrosis of the exocrine parenchyma, leading to exocrine pancreatic insufficiency and progressive endocrine failure leading to diabetes. Tropical calcific pancreatitis, an inflammatory condition of the pancreas, is usually associated with the pancreatic duct stones for which lateral pancreatico jejunostomy provides excellent results with acceptable early morbidity and mortality. Objective: To assess the post-operative complications of pancreatico jejunostomy in patients with pancreatic calculi. Methods: This was a descriptive type of prospective study. A total of 26 patients were included in the study between July 2011 to December 2011 in a BSMMU and other private hospitals of Dhaka who underwent lateral pancreatico jejunostomy for pancreatic calculi. Data were collected using a structured questionnaire and presented in tables by number, percentage, mean±SD, median. Results: This study was conducted to find out the efficacy and safety of lateral pancreatico jejunostomy in cases of pancreatic calculi. Highest proportion of the patients (n=26) are in the age group of 30-40 years (13 out of 26 number of patients. The mean age of the patients is 36.74. More than 64% of the patients were male. Female was found in 35% cases. Revealed that 3.84% of the patients were alcoholic. 96.15% of the patients (25 out of 26 patients) were non alcoholic. 30.76% (8 patients out of 26) is associated with gallstone disease.69.23% (18 patients out of 26) is not associated with gallstone disease. Upper abdominal pain was present in 100% patients. Steatorrhoea was present in 15.38% of the patients (4 patients out of 26).Jaundice predominated in 3.85% of the patients (1 patient out of 26). Shows that 34.61% of the patients (9 patients out of 26) developed post-operative morbidity, death occurred in 3.85% (1 patient out of 26). In our study 11.54% of the patients (3 patients out of 26) ............
Original Research Article
Determination of Antioxidant and α–Amylase Inhibition Properties of Alligator Pepper (Aframomum Melegueta): A Potential Therapeutic Against Diabetes Mellitus
Abdullahi J. Muhammad, Murtala Muhammad, Abdulmumin Yunusa, Tasiu A. Mikail, Maimuna M. Dalhatu, Ishaq Y. Habib, Shahida I. Sarki, Mariah S. Gwarzo, Nafisatu A. Muhammad, Rabitu Kabir Mustapha
EAS J Pharm Pharmacol, 2022; 4(3): 43-42
DOI: 10.36349/easjpp.2022.v04i03.001
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ABSTRACT
Diabetes is a chronic metabolic disease characterized by raised levels of blood glucose, which over time leads to serious damage to the heart, blood vessels, eyes, kidneys, and nerves. α-amylase Plays a major role in the digestion of starch and glycogen. Thus, inhibitors of this enzyme delay the breakdown of carbohydrates in the small intestine, thereby diminishing postprandial blood glucose in the diabetic patient. In this study, a DPPH radical scavenging activity and computational approaches were employed to uncover the potential of Aframomum Melegueta phytochemicals against type two diabetes mellitus mainly by molecular docking, molecular dynamic simulation, MMPBSA and ADMET analysis. The results show that it has high antioxidant properties. Molecular docking indicates that laurifolin, genkwanin and gulunalactone have good binding scores of -9.9 kcal/mol, -8.9 kcal/mol and -8.2 kcal/mol, respectively. And have interacted with at least two of the catalytic triads of α-amylase; Asp 300, Glu 233 and Asp 197. Molecular dynamic simulation results show that all the compounds are stable at the active site of the enzyme. Furthermore, MMPBSA analysis revealed they bind strongly with the binding energy of -21.77± 1.03 Kcal/mol, -17.82 ± 0.84 Kcal/mol and 15.07± 0.26 Kcal/mol for laurifolin, genkwanin and galanolactone. ADMET analysis indicated that all the ligands are water-soluble, drug-like and safe. This study shows that A. Melegueta extract has antioxidant properties and possess phytochemicals that can be exploited for further anti-diabetic drug development.
Original Research Article
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Nigeria is endowed with tremendous and unimaginable human and natural resources. Since its rise to nationhood, agriculture was the major driver of its economy. The discovery of crude oil at Oloibiri in the Niger Delta in 1956 and with the production of 5,100 Barrels per day, crude oil receipts replaced agriculture as the major source of revenue for the government. The country depended solely on oil which has made its economy vulnerable to external shocks, resulting from price variations in the global oil market. This situation has affected the performance of its budgetary spending and poor handling of economic diversification drives. It is against this background that this paper intends to explore the potentials of a neglected industry like the tourist sector, using Kalale and Boziya as viable tourism destinations for social and economic developments in Zamfara State and Nigeria at large. The paper initiated strategies for the improvements of these identified tourism locations for recreational benefits, income generation and the development of critical infrastructures among others in Kalale and Boziya. The methodologies adopted in the collation of data were oral interviews, fieldworks, observation, and use of relevant documentaries. Multidisciplinary approach, historical and archaeological surveys were also applied and undertaken. The findings revealed that Kalale and Boziya have the potentials for tourist attractions that will usher in a significant inflow of foreign reserve that will further boost the economy of Zamfara State and Nigeria, besides the capacity of the industry in employment generation, alleviation of poverty and social cohesion among several other advantages.
Original Research Article
ABSTRACT
The on-farm trials were conducted in three districts of west shewa zene, Oromia region, Ethiopia, to compare the performance of Promising hybrids under farmers field and promote one or two hybrids for possible release as commercial variety. Seven hybrids were evaluated using randomized complete block design (RCBD) in 2021 cropping season. The combined analysis of variance for three districts showed highly significant mean squares due to genotypes for all studied traits except ear position. Site*entry interaction showed significant mean variance only for grain yield (GY) indicating that, the performance of these genotypes were not consistent across sites for this trait. Hybrids SXH180174 and 3XH1900432 were the best performing genotypes for grain yield and some yield related traits. The single cross hybrid SXH180174 scored the highest grain yield (10.05 tons/ha) as compared to the checks and showed preferred plant and ear aspects. Accordingly this hybrid was recommended for variety verification trial stage for release as commercial hybrid in highland agro-ecology of the country.
Original Research Article
ABSTRACT
The paper examined the effect of assessment for learning strategy (AFLS) on Student’s Achievement and interest in Senior Secondary School Mathematics in Ondo State. The study employed quasi experimental research design involving the non-randomized prelest, postlest, control group. The population comprises all Senior Secondary II students in Akoko North East Local Government, Area of Ondo State. A sample size of 100 Senior Secondary II students from two public Secondary school was used for the study. The sample was randomly grouped into one experimental and control. Data were collected using Mathematics Achievement Test (MAT) (r=0.76) and Mathematical Interest Inventory (MII) (r =0.82). Two hypotheses were generated to guide the study. The findings revealed that there was significant effect of instrument on students’ performance and interest with a (F value 4.161 and p value 0.000) at 0.005 level of significance based on the findings, it was recommended that Assessment for learning strategy should be employed or adopted in teaching Secondary students to enhance their interest in mathematics.
ABSTRACT
Inclusive education connotes the non-discrimination of students with diverse and different learning and physical abilities staying in the same classroom to learn and study side by side. it involves the non-segregation of students and adapting them into appropriate general education classes in schools available within their immediate environment that gives them access to high quality instructions, interventions and assistance to meet up primary, secondary and tertiary academic curriculum irrespective of any physical challenge they may have. The implementation of inclusive education in Nigeria will inevitably create new and increased demands for special educators, as well as other stakeholders putting all hands on deck to make ensure special needs children have quality and inclusive education. With the growing number of special needs children in the society due to the prevailing economic, societal and family problems, there is urgent need for the full adoption and enforcement of the special needs and inclusive education law of the child right act in Nigeria. This means the development of schools curriculum to cater for inclusive educations in the country. Government should place emphasis on special educators who are also expected to make adaptations and accommodations to the inclusive curriculum, their instructional techniques and evaluation procedures, as well as cater for their classroom behavior and develop appropriate management styles. The specialists who are already engaged in inclusive education must be provided with sufficient instructional resources, while at the same time encouraged to continue their efforts to reach out to all learners. Inclusive education should be seen by the government as a basic human right and the foundation for a more just, equal and egalitarian society.