ABSTRACT
Background: The most prevalent kind of diabetes that results from insulin resistance is type 2. Hyperglycemia, polyphagia, polyuria, and polydipsia are the traditional trifecta of symptoms associated with this illness. The purpose of this study was to ascertain the impact of petersianthus macrocarpus ethanolic leaf extract on the lipid profile and haematological markers of streptozotocin-induced type 2 diabetic wistar rats. Materials and methods: Five groups of rats were used: non-diabetic, diabetic, untreated, glibenclamide-treated, ethanolic extract-treated, and 100 mg/kg body weight-treated. Results: The body weight of the rats treated with 100 mg/kg body weight increased, while the body weight of the rats treated with 50 mg/kg body weight decreased, according to the results. Conclusion: 100 mg/kg body weight was determined to be the least effective therapeutic dose, indicating the potential of ethanolic leaf extracts.

ABSTRACT
Aim: To determine the effect of ethylenediaminetetraacetic acid (EDTA), lactic acid and citric acid on root dentin microhardness. Materials and Methods: In this in vitro study, twenty freshly extracted anterior teeth were transversely sectioned at the level of cementoenamel junction. The middle third of each root is then horizontally sectioned into slices that are 4 mm thick to obtain a total of 20 dentin discs. Based on the chelating agent used, the samples were randomly divided into four groups- saline (control group), 17% EDTA, 20% lactic acid and 10% citric acid. Vicker’s indenter was used to test the microhardness of the dentin before and after treatment with the chelating agents for two minutes. Data was obtained and statistically evaluated using a one-way analysis of variance (ANOVA), paired – t test and Tukey’s post hoc test. Results: The microhardness values varied significantly among the groups. Citric acid and and lactic acid were less effective at reducing dentin microhardness. EDTA led to a higher reduction in microhardness. Conclusion: All the chelating solutions reduced the microhardness. Lactic acid showed less alteration in the hardness of root dentin than EDTA.

ABSTRACT
Aim of the study: To assess the knowledge and attitudes of anesthesia staff on the management of pain in the hospitals of Niamey. Patients an method: This was a multicenter descriptive cross-sectional study carried out in five hospitals in Niamey (Republic of Niger) from July 3rd to December 3rd, 2021. Were been included in the study, all the anesthesia staff who agreed to answer the questionnaire. The variables studied were: age, gender, seniority, sector of activity and qualification, definition of pain, different types of pain, the impact of pain on the body, tools used for assessment of pain, difference between acute and chronic pain, knowledge about analgesics, the practical attitudes of pain management. The data were intered and processed with Epi info 7.2 software and the Microsoft Office 2019 pack. Results: Our study concerned 106 agents from the anesthesia and resuscitation department of the hospitals that served as our study framework. There is a female predominance of 55.42% with a sex ratio of 0.80. The 45-54 age group was the most represented with 40.07% of cases. The average age of respondents was 44.95 ± 8.9 years. Anesthesia nurses were the most represented with 90.36%. The operating theatre unit was the most represented sector of activity with 85.54%. All the respondents knew the definition of pain. The different types of pains were known by 45.78% of respondents. The most used pain scales were visual analog scale (VAS) and verbal descriptor scale (VDS) respectively in 53.01 % and 12.05 % of cases. Tramadol and paracetamol were the mostly used analgesics respectively in 98.80 % and 97.59%. Intravenous morphine titration was known to 67.47% of the respondents. Only 18.07% of the respondents benefited from a training on the management of pain. Conclusion: The knowledge and attitudes of anesthetists on pain deserve to be updated through theorical and practical training to improve the management of pain in our hospitals.

ABSTRACT
This study aims to describe and analyze the influence of intellectual intelligence, emotional intelligence and spiritual intelligence on the performance of female employees at PT. Bank Rakyat Indonesia (Persero) Tbk Regional Officel Malang, as well as to find out the most influential variables on the performance of female employees. To answer the research problems, a questionnaire was distributed to 85 female employee respondents with age criteria </=45 years. Furthermore, the results of the questionnaire were analyzed using descriptive analysis and multiple linear regression analysis techniques, by first carrying out the feasibility test of the research instrument, besides that the classical assumption test was also carried out, hypothesis testing and the coefficient of determination (R2). The results of the analysis show that the description of the variables of intellectual intelligence, emotional intelligence, and spiritual intelligence has very good implications for work, and the performance of female employees is in the "good performance" category. Meanwhile, partially the intellectual intelligence variable has no significant effect on the performance of female employees, emotional intelligence, and spiritual intelligence have a significant positive effect on the performance of female employees at PT. Bank Rakyat Indonesia (Persero) Tbk, Regional Office Malang. The variable that has the greatest influence is emotional intelligence.

ABSTRACT
Physical Education Major in Colleges and universities is the main force to cultivate excellent physical education reserve talents in China. In order to improve the training quality of compound talents in physical education, this study takes the curriculum of physical education major in colleges and universities as the research object, and studies the curriculum structure, curriculum teaching mode, curriculum practice and curriculum evaluation of the curriculum of physical education major. The research shows that optimizing physical education curriculum based on OBE concept can meet the needs of physical education curriculum construction, deepen the curriculum reform of physical education, and help achieve the goal of training physical education professionals. However, based on the current research results, it is found that there are corresponding deficiencies in the implementation of each part. Therefore, this study puts forward the corresponding reform strategies according to the five contents emphasized by the OBE concept: everyone can succeed, personalized evaluation, proficiency, performance responsibility and ability standard. For the course structure, we should increase the types of elective courses and improve the proportion of technical courses; For the classroom teaching mode, adopt the flexible organization form of the course, update the design structure of the course and enrich the teaching methods of the course; For curriculum practice, we should pay attention to curriculum teaching practice and strengthen educational practice; For curriculum evaluation, comprehensive evaluation content and diversified evaluation methods are adopted.