AIM: Toxicity of colloidal silver is an important issue in the medical sector. The product manufactured by Edigalf Services had been submitted to the FDA in Ghana for registration as homeopathic immunecare after animal studies. This current paper addresses the total concentration or power dose of the product colloidal silver life water. Method: In Addressing the FDA position on the total concentration of the said product submitted for registration. The Manufacturer reviewed the previous duration of usage from two weeks to be taken (15ml) three teaspoonful three times daily on the label previously submitted. The new reviews on the label have the duration for twelve days (12) only and to be taken one teaspoonful (5ml) daily. Result: From the calculation, the total concentration of the product, colloidal silver life water for twelve(12)days duration is 600mcg which still falls within the ‘safe grade’ of the Environmental Protection Agency(EPA)-IRIS Report-Silver. Conclusion: We report that, based on the total concentration or power dose for twelve (12) days, the product colloidal silver life water is within the acceptable grade of safety based on the Environmental Protection Agency (EPA)-IRIS Report on Silver.