Introduction: Breast cancer is the most common cancer in the world, especially in Cameroon, where in the absence of a national screening program for this condition, several free campaigns are associated with individual screening, through the practice of mammograms. The aim of our study was to specify the lesional characteristics of mammograms in women at Douala Gynaeco-Obstetric and Pediatric Hospital (DGOPH). Methods: This was a retrospective and descriptive cross-sectional study in which we extracted data from mammograms performed in women between January 2019 and December 2020, at DGOPH. Results: Out of 247 records, the most represented age group was that of 50-60 years (36.84%). The most common indication for examination was collective screening (45.34%). Micro-calcifications were the most frequent lesions (23.08%), especially of the benign type. 39.27% of mammograms were reported as normal. Conclusion: Although patients aged 50 to 60 are the most represented in our study, coming for mass screening, and presenting the vast majority of normal results, it remains important to educate relatively younger women about the importance of having a mammogram, especially since it is observed in hospital studies that an increasing proportion of young women present with breast cancer in our context.