The Covid-19 pandemic has caused panic and a global mental health burden as well as provides potential negative impacts on the health workers who are at risk of experiencing psychological disorders as well as other mental health symptoms. This study aims to determine the mental health of health workers who worked during the Covid-19 pandemic in hospitals. Methods: This cross-sectional study was conducted online in December 2021 on 213 health workers serving at a Regional General Hospital. Results: The results showed a significant relationship between age, income, the number of children, history of illness, employment status, and other occupations with the incidence of depression in health workers. Moreover, there was a significant relationship between gender, history of illness, and years of service with the incidence of anxiety. A significant relationship was also found between a history of illness and other occupations with the incidence of stress in health workers. Conclusion: All variables had no significant relationship with the mental health of health workers; therefore, it is necessary to carry out an initial screening on the major cause of mental health problems in health workers.