Infectious bursal disease (IBD) is a significant viral infection of poultry caused by IBD virus (IBDV), resulting in severe economic losses. In this study, we reviewed gross lesions associated with IBD diagnosed at the Avian Clinic, Veterinary Teaching Hospital, Ahmadu Bello University, Zaria, Nigeria, from January 2013 to December 2023. Data were collected from the record book of the Avian Clinic, entered into Microsoft Excel sheet, cleaned and exported to Statistical package for Social Sciences (SPSS version 27) for analyses. Outcomes revealed that IBD constituted 13.0% of the 1,922 cases recorded, with the highest cases in 2023 (33.9%) and 2022 (33.8%), and the lowest in 2013 (5.8%). Gross lesions were mostly (88.4%) observed in the bursa of Fabricius, and these included enlargement (65.1%), turgidity (60.6%), oedema (17.3%), and haemorrhages (33.7%). Other affected organs included the pectoral/thigh muscles (73.9%) with congestion and haemorrhages (47.8% each), and liver (65.5%) with congestion (28.5%) and pallor (27.3%). There were haemorrhages in the proventriculus (53.8%), ventriculus (8.4%), proventriculus-ventriculus junction (10.0%), duodenum (50.6%), jejunum (16.5%), ileum (11.2%), and caecum (9.2%) and trachea (27.3%), and lung congestion (35.7%). The air sacs were cloudy (21.7%) and showed air sacculitis (4.0%). The kidneys were congested (15.7%) and pale (18.9%), with urates (2.0%); the gallbladder was distended with bile (16.1%) and congested (2.4%). This study emphasises the multi-organ involvement in IBD, thus, the need to strengthen control measures. The findings contribute valuable information on IBD pathology and can assist veterinarians and poultry farmers in improving disease management and prevention.