: Background- Intra-arterial cannulation for invasive blood pressure monitoring is required in patients with shock. However in these patients it is difficult to pass the cannula because of difficulty in palpation of artery. Few tools like ultrasound guidance and Doppler auscultatory assistance are available to locate the artery in such difficult cases. However use of ultrasound requires practical as well as operator knowledge. Hand held fetal Doppler auscultatory assistance device is an easily available tool that can be effectively used for arterial cannulation in patients with shock. Method: This is a prospective study conducted in 100 patients who were admitted to Intensive care unit with shock. Here intra-arterial cannulation was done with the help of hand held Doppler ausculatory assistance device by an inexperienced operator. We observed the ease of cannulation indicated by number of attempts, number of cannulas used, failure to cannulate and post cannulation complications in difficult conditions like shock, by inexperienced operators. Result - In 72 patients cannula was placed in first attempt, 12 patients required 2-3 attempts. In 10 patients though artery was located cannulation was unsuccessful and different site was cannulated. These 10 patients required more than 2 cannula as they were damaged during the procedure. In 6 patients neither artery was located satisfactorily nor were we able to cannulate the artery. Conclusion - A simple hand held Doppler ascultatory assist device can be used to cannulate the artery in difficult cases even by inexperienced operator where palpation of artery is difficult.