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Acute Adrenal Insufficiency in a Pregnant Woman at 34 Weeks of Gestation in the Gyneco-Obstetric Intensive Care Unit: A Case Report

DOI : https://doi.org/10.36349/easjacc.2025.v07i03.003
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Acute adrenal insufficiency (AAI) is a rare but potentially life-threatening endocrine emergency, particularly challenging in pregnancy due to overlapping symptoms with physiological changes and increased maternal-fetal risks. This report highlights the case of a 35-year-old woman with chronic adrenal insufficiency, presenting at 34 weeks of gestation with acute decompensation. Symptoms included severe abdominal pain and tonic-clonic seizures, confirmed by low cortisol levels and laboratory abnormalities. Prompt administration of hydrocortisone and emergency obstetric care ensured favorable maternal and fetal outcomes. The case underscores the importance of rapid diagnosis, appropriate glucocorticoid therapy, and a multidisciplinary approach to managing AAI in pregnancy. It also highlights the need for vigilant monitoring of pregnant women with chronic adrenal insufficiency to prevent decompensation. Early intervention is critical to reducing maternal and fetal morbidity and mortality.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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