EAS Publisher | Thyrotoxic Crisis in a Pregnant Woman at 16 Weeks of Gestation in the Gyneco-Obstetric Intensive Care Unit: A Case Report

Thyrotoxic Crisis in a Pregnant Woman at 16 Weeks of Gestation in the Gyneco-Obstetric Intensive Care Unit: A Case Report

DOI : https://doi.org/10.36349/easjacc.2025.v07i03.004

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Thyrotoxic crisis during pregnancy is a rare but life-threatening condition, most commonly associated with Graves’ disease. This case report details a 25-year-old primigravida at 16 weeks of gestation who presented with severe thyrotoxicosis. Symptoms included tachycardia, hyperthermia, and fatigue. Laboratory findings confirmed suppressed TSH and elevated free T4 levels. Immediate treatment with beta-blockers and antithyroid drugs stabilized the patient. Pregnancy alters thyroid physiology, increasing the risk of hyperthyroidism complications such as miscarriage, preterm birth, and preeclampsia. Treatment involves antithyroid medications, with PTU preferred in the first trimester due to MMI’s teratogenic risks. Close monitoring of thyroid hormone levels and fetal well-being is critical. Despite the severity of the initial presentation, the patient’s pregnancy progressed without complications, highlighting the importance of early and aggressive management.

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