This study investigates the influence of advertising on consumer brand preferences in Central Equatoria State, focusing on Juba. Employing a mixed-methods approach that combines quantitative surveys and qualitative interviews, the research explores how diverse advertising channels such as social media, television, radio, and print media affect consumer perceptions, loyalty, and purchasing behavior. The findings indicate that emotionally engaging and culturally relevant advertisements significantly enhance brand preference; 68% of respondents reported that campaigns resonating with local symbols and narratives are more memorable and persuasive. Social media platforms like Facebook and WhatsApp emerged as the most influential digital channels, reaching approximately 72% of urban youth aged 15–35, while television remains a primary information source for 60% of respondents across age groups. Despite the growing dominance of digital media, traditional outlets like radio continue to play a vital role, especially among rural and lower-income populations, with over 70% of households tuning in regularly. The study emphasizes that personalized and culturally tailored advertising strategies outperform generic approaches in Juba’s emerging market, fostering stronger emotional connections and higher brand loyalty reported by 55% of participants as a key factor in their purchasing decisions. Given the economic instability and low consumer purchasing power, integrating local cultural elements and segmenting audiences based on socio-economic status can enhance advertising effectiveness. The research recommends prioritizing digital channels, particularly social media, and developing culturally sensitive campaigns to build trust and loyalty. Additionally, promoting media literacy programs can empower consumers to make informed choices. Overall, targeted, emotionally resonant, and culturally relevant advertising strategies are crucial for strengthening brand presence and market growt