Combined gynecologic and general surgical procedures are increasingly performed due to the need to address coexisting pelvic and abdominal pathologies in a single operative session. This review aims to synthesize existing evidence regarding postoperative complications associated with these combined approaches. A comprehensive literature search was conducted across PubMed, Scopus, and Cochrane databases for studies published between January 2019 and October 2019. Eligible studies included randomized trials, cohort studies, and case series that reported on complication rates, risk factors, and outcomes in women undergoing combined surgeries. The review identified a spectrum of complications, ranging from minor wound infections to significant morbidities such as venous thromboembolism and organ injury. Notably, infection rates were higher in combined procedures compared to single-discipline surgeries, likely due to prolonged operative times and more extensive dissection. Conversely, some studies reported comparable overall morbidity when meticulous perioperative protocols were employed. This review highlights the need for standardized guidelines on patient selection, intraoperative strategies, and postoperative monitoring. Future research should focus on prospective multicenter studies to better characterize predictors of adverse outcomes. The findings underscore that while combined procedures can reduce overall hospitalization, they may also confer increased complication risks, warranting careful multidisciplinary planning.