This study aimed at assessing biometric, thermo-physiology and blood profile of Noiler birds under intensive management in Lafia. The study was conducted at the Poultry Unit of the Teaching and Research Farm of the Livestock Complex of College of Agriculture, Science and Technology Lafia, Nasarawa State. A total of one hundred (100) Noiler birds of equal number of both sexes at six weeks of age were procured from the brood and sales farmers of reputable Poultry Farms in Jos, Plateau State Nigeria. Body weight, six biometric traits and thermo-physiological traits were measured on the birds on four-weekly basis for six (6) months (January 2025 – June 2025). 2ml of blood samples were taken from the jugular veins of ten (10) birds for blood profile analysis. The General Linear Model was adopted for the analysis. Body weight and biometric traits of the male birds were higher (P<0.05) than their female counterparts. Female birds recorded higher (P<0.05) rectal temperature and respiratory rate as well as white blood cell and mean corpuscular volume than their male counterparts. Male birds recorded higher (P<0.05) low density lipoprotein than their female counterparts. The highest (P<0.01) significant positive correlation for male and female birds were observed between body weight vs breast circumference (r = 0.894) and total leg length vs foot length (r = 0.773. Prediction of body weight was at the optimal ages of 28.85 and 29.50 weeks for male and female birds. The findings of this study would provide an understanding of sexual differences in terms of meat production, adaptation as well as the well- being of the birds.