Dupuytren's disease is a chronic fibroproliferative disorder of the palmar fascia leading to progressive flexion contractures of the fingers, most often affecting the ring and little fingers. This condition predominantly affects men over the age of 50 and has a multifactorial etiology involving genetic predisposition and environmental risk factors such as manual labor and alcohol consumption [1, 2]. We report four clinical cases treated at the CHU de Rabat to illustrate the spectrum of presentations and therapeutic outcomes. All patients underwent surgical management with open fasciectomy. The procedures resulted in functional improvement without significant complications. A structured postoperative rehabilitation program was followed, contributing to satisfactory recovery. Non-surgical treatments such as collagenase injections may be effective in selected early-stage cases but were not applied in our series [3, 4]. The choice of therapy must be tailored according to disease severity and patient function. Surgical excision remains the standard in advanced stages, especially when deformities impair daily activities [2-5]. Follow-up is essential to monitor recurrence, which remains a challenge despite optimal management. This series emphasizes the importance of early diagnosis, patient education, and coordinated multidisciplinary care in optimizing outcomes.