Introduction: Anesthesia outside the operating room develops in various areas requiring a calm, relaxed and painless patient. The anesthetist-resuscitator intervenes thus outside the block to ensure appropriate care. The main objective of this work is to analyze anesthetic practices performed outside the operating room over a period of 30 months. Methodology: This is an observational, prospective and cross-sectional study with analytical aim, conducted over 30 months (from June 4, 2018 to November 30, 2020) in the Anesthesia-Intensive Care department of the University Hospital of Angré. It includes all patients, regardless of age or gender, who required sedation for an imaging or endoscopy procedure. Results: The majority of out-of-block sedations involved infants, children and young adults. The sex ratio of 1.15 in favor of women. Medical imaging examinations were the main indication for sedation (60.62%). Propofol was the most used induction agent in 57.03% of cases (n = 223). Anesthetic maintenance was required in 172 patients (43.99%), with propofol also predominantly used (n = 157; 40,15 %). The majority of patients (97.67%) were able to return home after the procedure, while 0.51% (n = 2) required a transfer to intensive care. Conclusion: Out-of-block sedation is mainly performed in children, using imaging, with propofol as the main induction agent.