Heavy metal pollution in the Niger Delta's aquatic ecosystems, driven largely by crude oil exploration and industrial activities, poses significant ecological and human health risks due to the persistence and bioaccumulation of elements such as lead (Pb) and cadmium (Cd). This study aimed to assess the concentrations of Pb and Cd in water, sediment, and the aquatic macrophyte Eichhornia crassipes (water hyacinth) from Kolo Creek, Bayelsa State. Samples were collected from three locations along the creek over two months and analyzed using an atomic absorption spectrophotometer (AAS). The results revealed detectable levels of both metals across all matrices, with sediment samples showing the highest concentrations (Pb: 1.608–1.863 mg/kg; Cd: 0.137–0.150 mg/kg), while lower levels were found in water hyacinth (Pb: up to 0.004 mg/kg; Cd: 0.0028–0.0040 mg/kg). Statistical analysis showed strong positive correlations between metal concentrations in the different compartments. In conclusion, the study confirms that Eichhornia crassipes is an effective bioaccumulator of heavy metals, underscoring the significant long-term ecological risk posed by elevated sediment metal levels and highlighting the need for stricter discharge regulations and the adoption of phytoremediation strategies.