Background: Carpal Tunnel Syndrome (CTS) is a compressive neuropathy of the median nerve that commonly affects manual laborers, including traditional ikat weavers. Repetitive hand movements and prolonged wrist flexion contribute significantly to CTS occurrence. Objective: To analyze the relationship between working period and Carpal Tunnel Syndrome complaints among ikat weaving workers in Bomari and Boradho Villages, Ngada Regency. Methods: A cross-sectional analytic study was conducted from June to August 2024 among 50 ikat weaving workers meeting inclusion and exclusion criteria. Data collection used structured questionnaires and the Boston Carpal Tunnel Questionnaire (BCTQ). The Chi-Square test with a significance level of p < 0.05 was applied to determine the relationship between working period and CTS complaints. Results: Most respondents (66%) had mild to moderate CTS complaints. A statistically significant relationship was found between the working period and CTS complaints (p = 0.012). Workers with more than 10 years of weaving experience had a higher likelihood of developing CTS symptoms. Conclusion: There is a significant relationship between working period and CTS complaints among ikat weaving workers. Early ergonomic interventions and preventive education are essential to reduce CTS risk in traditional weaving communities.