Objective: To contribute to improving the management of postoperative pain by nurses in the Anesthesia and Intensive Care Unit at Donka National Hospital. Patients and Methods: This was a descriptive cross-sectional study lasting six (6) months from August 2024 to February 2025. We included in this study all nurses working in the operating room and post-operative care units who gave their consent to participate in the study. Results: During the study, 50 out of 51 nurses responded to the questionnaire, representing a participation rate of 98%. The average age was 29 ± 4 years, with a predominance of 25-30 year olds (42%) and a male majority (sex ratio 1.38). State-registered nurses accounted for 72% and those with 1-5 years of professional experience accounted for 60%. Among them, 56% had received training in pain management, compared to 44% who had not. 68% were familiar with pain assessment scales, while 32% were not. Among participants using scales, 52.9% used the numerical scale (EN 0-10) and 26.5% used the visual analog scale (VAS). For drug management, 62% used tramadol, 20% used morphine, and 18% used paracetamol. Conclusion: Continuing education and increased awareness are necessary to optimize postoperative pain management.