Caregiver burden is a significant concern in the management of individuals with cognitive impairment and Alzheimer’s disease, particularly as functional abilities decline. This study aimed to examine the relationship between Instrumental Activities of Daily Living (IADL) performance and caregiver burden among caregivers of older adults. A total of 60 caregivers participated in the study. Descriptive statistics revealed a mean IADL score of 3.10 (SD = 1.311), indicating moderate functional dependence among care recipients, and a mean Caregiver Burden Assessment (CBA) score of 52.27 (SD = 6.822), reflecting moderate to relatively high perceived burden. Pearson correlation analysis demonstrated a weak positive correlation between IADL and CBA scores (r = .143); however, the relationship was not statistically significant (p = .276). These findings suggest that functional dependence in instrumental daily activities alone may not significantly predict caregiver burden in this sample. The results highlight the multifactorial nature of caregiver burden and underscore the need to consider additional psychological, social, and contextual factors when addressing caregiver well-being. Further research with larger samples is recommended to better understand the determinants of caregiver burden.