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Management of an Adenocarcinoma of the Head of the Pancreas Classified as Borderline: About a Case

DOI : https://doi.org/10.36349/easjms.2026.v08i03.006
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Adenocarcinoma of the pancreas (AP) accounts for 90% of pancreatic tumours and is expected to become the second leading cause of cancer deaths in Europe and the United States by 2030. Its incidence has been increasing significantly for several years. The curative treatment of adenocarcinoma of the pancreas until recently relied mainly on surgery, which is only feasible in a limited number of cases due to the high frequency of loco-regional (lymph node and vascular) and metastatic extension, particularly hepatic. Chemotherapy has both curative and palliative indications. In recent years, systemic induction treatment has become the reference for borderline classified tumors. The results of the first prospective randomized phase II studies confirm the interest of a systematic induction treatment. We report the case of a 57-year-old woman, diagnosed with an adenocarcinoma of the head of the pancreas classified as borderline. Induction chemotherapy was performed, followed by reassessment and cephalic duodenal-pancreatectomy surgery. The aim of this work is to present the diagnostic and therapeutic approach adopted for a borderline tumor of the pancreas head.

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Professor Thomas Count Dracula, MD, PhD

Distinguished Professor of Haematology Head — Experimental, Historical & Sensory Haematology Vlad the Impaler University, Wolf’s Lane, Wooden Stakes Grove 666, Transylvania.

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