Environmental sanitation and waste management are critical components of public health, environmental sustainability, and urban development. In Calabar, Nigeria, rapid urbanization and infrastructural challenges have exacerbated issues related to poor environmental sanitation, improper waste disposal, pollution, and disease outbreaks. The aim of the present study was to assess the knowledge, attitude and perception (KAP) of community members in Calabar regarding environmental sanitation and waste management. Three research questions, three objectives and one hypothesis were formulated to guide the study. Literature was review based on major research variables. Health belief model and unitary human being model were used. The study employed a descriptive cross-sectional design. A multistage stage sampling technique was used to select a total of 301 residents from 2 randomly selected council wards in Calabar municipal. The streets from where data was collected were further selected via a convenience purposive method. Data were collected using 54-item Adopted questionnaires validated for content and reliability. Data collected was coded using SPSS version 25.0 and analysed using descriptive statistics and multivariate regression at p value 0.05, significance level. Findings revealed a high level of knowledge (mean = 2.96), positive attitude (mean = 2.92), and favourable perception (mean = 2.89) of environmental sanitation and waste management. Moreover, hypothesis test indicates F-value of 9.762 for the relationship between variables, because the p-value 0.000 is less than 0.05 level of significance at 3 and 298 degrees of freedom, there was significant relationship between the variables. This indicates that increased knowledge, positive attitude and perceptions are associated with responsible waste management behaviours. The study emphasized the need for continuous community education, infrastructural development, and policy enforcement to sustain positive environmenta