ABSTRACT The study was undertaken to determine biometric characterization of locally adapted Muscovy ducks in Nasarawa South Agricultural Zone. Three hundred matured Muscovy ducks were randomly selected from three randomly selected LGAs in the Nasarawa south Agricultural zone and used for the experiment. Body weight and body linear measurements as well egg qualities characteristics were determined across lafia doma and Awe Local Government Area of Nasarawa South. The data collected were analysed using one way analysis of variance (ANOVA) of the SPSS statistical package version 21. The results obtained indicated that, birds from Awe (location 3) had significantly (P<0.05) higher body weight (2.22±0.07 kg), wing length (40.74±0.73cm), tail length (18.93±0.26cm), egg weight (66.79±0.64g), albumen length (10.20±0.17mm) and albumen width (6.60±0.16mm) compared to those from locations 1 and 2 (Lafia and Doma). However, birds from Lafia (location 1) had significantly (P<0.05) higher chest circumference (14.76±0.26cm) and comb length (2.16±0.46cm) compared to birds from Doma and Awe (locations 2 and 3). Similarly, birds from locations 1 and 2 (Lafia and Doma) had significantly (P<0.05) higher shank length (5.91±0.16cm and 5.93±0.17cm, respectively) toe web (5.97±0.14cm and 5.92±0.14cm, respectively) and egg length (6.13±0.02mm and 6.07±0.02mm, respectively) compared to birds from location 3 (Awe). From the finding of this research, it was concluded that location have effect on Muscovy duck as such selection of these birds should be location based and subsequently be cross bred to utilise heterosis.
ABSTRACT This abstract describes the Genomic Impact of science on society. How progress in Genomic has provided us enormous benefits for designing drugs like AZQ to treat brain cancer and at the same time raised some serious ethical problems. Instead of finding new treatment of cancers by the old trial-and-error methods, we are developing rational drug design to treat cancers based on the genetic make-up of a specific disease. Sequencing Human Genome has identified 24,000 genes that provides total information to make us. In our genome, we carry 16,000 good genes that code for good proteins that keep us healthy. There are 6,000 bad or mutated genes responsible for causing six thousand different diseases. There are 2,000 Pseudogenes that have lost their functions because they are no longer in use. The 6,000 mutated genes are damaged by radiations, chemical or environmental pollution, viral infection or genetic inheritance. The mutated genes code for wrong proteins which make them responsible for causing diseases. For example, when we sequence a bad gene and compare with the Reference Sequence, we could easily identify the location of the mutated gene on a specific chromosome. The rational drug design requires that we synthesize drugs based on the genetic make-up of the sequence. AZQ (US Patents 4,146,622 and 4,233,215) was rationally design to attack Glioblastoma, the Brain Tumor. This abstract present not only the discovery of AZQ, but also presents some possible solutions to serious ethical problems.
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