ABSTRACT
Introduction: Job satisfaction is one of the most important factors in job success, especially in nurses and hospital staff who play a significant role in promoting community health as human resources. Therefore, this study was conducted to evaluate the job satisfaction of emergency staff at Shiraz public hospitals. Methods: This cross-sectional study was carried out on 400 nurses working in the emergency departments of 5 hospitals in Shiraz. The sampling from the emergency departments was done randomly. The data were collected using the JDI questionnaire (Job Descriptive Index), and the t-test and ANOVA were also used to analyze the data. Results: 274 individuals in this study (68.5%) were female and 211 ones (52.8%) were married. There was no significant relationship between job satisfaction and gender, employment status, organizational position, and marital status (p> 0.05). According to the ANOVA results, there was a significant relationship between job satisfaction and educational level (p = 0.006), work experience (p = 0.014) and income (p = 0.003). Conclusion: Based on the results of the present study, the individuals with higher work experiences, higher education and higher income had higher job satisfaction as well.

ABSTRACT
A disturbed thyroid check-up is a frequent reason for consultation in endocrinology. The typical situations of hypo or hyperthyroidism encountered lead to classical etiological investigations, to define whether the cause is central or peripheral. In certain unusual situations, the profile encountered may be atypical. We report the case of a 6 years old girl hospitalized for a homogeneous goiter, a tachycardia evolving for a year without thyrotoxicosis or compression. There was strong consanguinity in the family and the mother had a history of thyroidectomy. The assessment found a normal TSH with a high LT4 level, and her mother had the same hormonal profile. Neck ultrasound found a homogeneous goiter with normal vascularization and thyroid scintigraphy, a moderate goiter with very intense fixation, without nodules. Biological examinations found normal prolactin and cortisol levels. The pituitary MRI was without abnormality. The diagnosis of central hormone resistance syndrome was retained. This autosomal dominant transmission syndrome is a rare entity with poor symptomatology. It is important to think about it as a differential diagnosis of a thyreotropin-secreting pituitary adenoma when it results to an increased peripheral hormone level with a normal or elevated TSH, especially in patients with strong consanguinity. The diagnosis is made by genetic tests but it is rarely practice. The treatment is not codified. It ranges from abstention to thyroidectomy and it depends signs of thyrotoxicosis are identified.

ABSTRACT
Diabetic foot is one of the most common complication that occurs in patients with diabetes and various new concepts on this disease have been developed in past few years. Amit Jain’s system of practice is one such new modern diabetic foot surgery system that was developed by the author from India. This article highlights few contributions done by the author in diabetic foot field and also in surgery.

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Background: This study investigated gender variation in digit ratios of the Bini ethnic group. The study had an analytical cross-sectional design with volunteers age ranging from 18-60 years. For the purpose of this study, an individual was considered to be a Nigerian of a particular ethnic group if the parents and four grandparents are of the same ethnic group. Materials and Methods: Purposive sampling method was used for the study. The selection and collection of required parameters relied on informed consent of volunteers. This was done by giving them a copy of the informed consent letter which was signed and dated. A total of 1,200 subjects (Ikwerre 400, Bini 400, Igbo 400) subjects were recruited for the study. The fingerprints were obtained using print scanner (Hp G3110 Photo scanner). Results and Discussion: The mean digit ratio across the three ethnic groups indicated that the Ikwerre had the following on the left 0.99±0.03; Bini 0.98±0.05 while the Igbos had 0.88±0.02. On the right hand, the mean digit ratio showed that the Ikwerre had 0.98±0.04; Bini 0.98±0.04 while the Igbos had 0.87±0.04. The Ikwerre ethnic group was shown to have a digit ratio closer to the Bini ethnic group than the Igbos and there was no statistical significance (p>0.05) in the comparison of digit ratio between Bini and Ikwerre ethnic groups. There was statistical significance (p<0.05) in the comparison of digit ratio between the Igbos and Ikwerres. Conclusion: The mean of the digit ratios for the Bini people is closer to that of the Ikwerre people than the Igbos. Statistical comparison of the ethnic groups showed that the difference between the Ikwerre and Bini people was not significant meaning that they possibly have ancestral relationship whereas that of the Igbos and Ikwerre people was statistically significant showing that they have a reasonable difference large which ultimately may translate in them not having ancestral relationship.

ABSTRACT
Polycystic ovarian syndrome (PCOS) is a common female endocrine disorder with prevalence ranging from 2.2 to 26 percent among reproductive age women between 15 to 44 years with or without children. So the aim of the study is impact of socioeconomic status on polycystic ovarian syndrome among reproductive women. Material and Methods: A descriptive study was conducted among 60 reproductive age group women in rural areas of Bukkarayasamudram Mandal, Anantapuramu District. An interview schedule was used for data collection. A simple random sampling technique was used for selection of sample. Results: The results of the study population comprised of 60 reproductive age women. The majority of represents 30 (50 percent) are getting < Rs.10000 per month family income. The analysis of the symptoms experienced by PCOS women showed that 78.3 percent gained weight,82 percent experienced irregular bleeding,56 percent acne problems,64 percent pelvic pain,25 percent had metabolic disorders, a few represents 7.3 percent had infertility,36.7 percent had depression and anxiety, 65 percent hirsutism. Conclusion: The results of study revealed that women who belongs to low socioeconomic status in childhood are at increased risk of PCOS, but this risk is limited to who attain higher education. More research is needed to determine the childhood socioeconomic factors that might influence the risk of life style modifications associated with upward life mobility play a vital role on reproductive age group women with symptoms and diagnosis of PCOS.

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To determine and classify the various types of poisoning deaths as seen at Andhra Medical College, KGH Mortuary, Visakhapatnam City. Materials and Methods: This is a prospective study of deaths due to poisoning seen in the Department of Forensic Medicine & Toxicology, Andhra Medical College, Visakhapatnam City over a 1year period (January 2017 ‐December 2017) as postmortem reports, inquest reports and hospital records. Observations: Poisoning is one of the commonest methods of committing suicide especially in developing countries like India. A total of 1646 autopsies were done during the period. One hundred and thirty-two cases representing 132 cases (8.02%) of all bodies received by the mortuary were deaths due to poisoning. Organophosphate compounds were the most commonly 63.6 % abused substance. The common motive of poisoning was suicidal 82.6 % with male to female ratio 4.73:1 Peak incidence was observed in the age group 21-40 years. Type of poison consumed, socioeconomic status and place of household are also ascertained. Conclusion: This study shows the pattern of poisoning deaths in Visakhapatnam and this preliminary data will provide a baseline for future research and help in formulating policies to prevent deaths due to poisoning.

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Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a leading cause of hospital admission and mortality in India, yet hospital-based data on clinical profiles and modifiable risk factors remain limited. Objective: To characterise the clinical profile of patients admitted with AECOPD and to identify risk factors associated with exacerbation severity and adverse outcomes. Methods: A hospital-based observational study was conducted at TRR College of Pharmacy over five months (August–December 2019), enrolling 48 patients with spirometry-confirmed COPD admitted with AECOPD. Demographic, clinical, laboratory, and microbiological data were collected using a predesigned proforma. Exacerbation severity was graded using GOLD 2023 criteria. Results: The mean age was 63.4 ± 9.8 years, and 79.2% were male. Breathlessness (100%), productive cough (85.4%), and fever (75.0%) were the predominant symptoms. Current or ex-smoking was reported by 81.3%, biomass fuel exposure by 35.4%, and prior pulmonary tuberculosis by 22.9%. Elevated CRP (>6 mg/L) was present in 87.5%, and sputum culture was positive in 58.3%, with Pseudomonas aeruginosa (32.1%) and Klebsiella pneumoniae (21.4%) predominating. Frequent exacerbators (≥2 in the preceding year) constituted 41.7% and had significantly higher CRP (p = 0.012), lower FEV₁% predicted (p = 0.008), and longer hospital stay (p = 0.003). Conclusion: AECOPD in this cohort was characterised by advanced age, male predominance, high infective burden, and substantial exposure to non-smoking risk factors including biomass fuel and prior tuberculosis. Frequent prior exacerbations, elevated CRP, and low FEV₁ were significant risk factors for adverse outcomes.