ABSTRACT
Ethosomes are novel lipid vesicular carriers containing a relatively high percentage of ethanol andthe novel approach for the current drug delivery as a transdermal drug delivery system which is employed for the assessment of the targeted drug to the site of action. There are many application in the development of the formulation for the better release to the systemic circulation. The therapeutic effect of these category of formulation totally depends upon the medium of the drug release, in which we can observe the amount of drug in the formulation and drug released to the site of action.Ethosomes are vesicular carrier comprise of hydroalcoholic orhydro/alcoholic/glycolic phospholipid in which theconcentration of alcohols or their combination is relativelyhigh.Ethosomes can entrap drug molecule with variousphysicochemical characteristics i.e. of hydrophilic, lipophilic,or amphiphilic. These formulations are better alternative of oral drug delivery in that patients, those cannot take orally.
ABSTRACT
Background: Because the Pharmacological knowledge of nursing students depend on the expertise of the Pharmacology instructors, they must possess an in-depth knowledge of Pharmacology and excellent teaching skill in order to teach effectively. Our study was designed to assess and compare the quality of teaching pharmacology between a Pharmacist Pharmacologist and the Nurse Pharmacologist Materials and Methods: The study was conducted using a comparative, cross-sectional design. A questionnaire was administered to 95 nursing students who were asked to assess the teaching performance of a nurse Pharmacologist and a Pharmacist Pharmacologist based on 4 pre-defined performance indicators. Data was processed using Excel 2010 Version. Results: 80 (84.22%) of the study population had interest in Pharmacology while 15 (15.78%) were not interested. 68 (71.57%) of the nursing students preferred the Nurse Pharmacologist and 27 (28.43%) preferred the Pharmacist Pharmacologist. Conclusions: The Nurse Pharmacologist was a more competent Lecturer than the Pharmacist Pharmacologist. The students preferred the Nurse Pharmacologist to the Pharmacist Pharmacologist.
Research Article
A Global Public Health Emergency: COVID-19
Shadab Ali, Anjali Sahu, Prerana Sahu, Harish Sharma, Manasi Gulati, Sindhu Anil Menon, Shailaja Anik and Gyanesh Kumar Sahu
EAS J Pharm Pharmacol, 2020; 2(4): 110-128
DOI: 10.36349/easjpp.2020.v02i04.003
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ABSTRACT
A highly contagious disease COVID-19, caused by SARS-CoV-2. The World Health Organization has declared the continuing outbreak to be a global public health emergency. Coronaviruses (CoVs) are a major group of viruses known to be responsible for wide spectrum of diseases in numerous species. The CoVs affecting human population are referred to as human coronaviruses (HCoVs). They lead to multiple respiratory diseases, such as pneumonia, common cold, bronchitis and respiratory syndrome. This review systematically summarizes the epidemiology, clinical characteristics, diagnosis, myths and facts, globally scenario and treatment of COVID-19.
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Aim: Phyto-gynecology is under-researched and explored in the Ghanaian Traditional Medicine Industry. Many Traditional Medicine Practitioners in Ghana make claims of their breakthrough in helping couples to give birth; yet, unable to justify their claims with one peer reviewed article. This paper therefore discusses the significant breakthrough of fertility management in five patients at Givers Scientific Hospital, Accra, Ghana, known for their strides in phyto-gynecology. Method: The investigator reviewed medical history of two patients based on their folders; before and after treatment between 2018-2019 periods. Confirmation of cyesis was also conducted based on their Pre and Post Pelvic ultrasonography. Result: There is evidence of cyesis post treatment at Givers Scientific Hospital based on the patients’ Medical Records. Conclusion: Natural birth method should be extensively researched and explored in the medical community to provide an alternative means of conception for patients.
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Aim: Hibiscus Sabdariffa Tea has received media publicity in recent times due to its ability to reduce blood pressure. The plant has been extensively researched as an alternative to help control high blood pressure, but yet, not much research had been conducted in Ghana on its antihypertensive properties. The objective of this study was to examine the antihypertensive effects of H. sabdariffa (hibiscus tea) with the brand name Nyarkotey Tea approved by the FDA in Ghana for cardiovascular Health and general wellbeing. Method: An observational study was conducted in one male hypertensive patient aged 33years with systolic pressure 180mmHg and diastolic pressure 120mmHg but not taking any pharmaceutical hypertensive drug. He was monitored for a day with the dosage, two tea bags in 500ml water boiled for 5 minutes three times. Result: After the third dosage, His blood pressure reading was monitored in the evening. His systolic pressure fell to 150mmHg and diastolic reading also fell to 100mmHg. His systolic pressure had 30 point reduction whilst his diastolic pressure had 20point reduction. Conclusion: This is the first observational study in Ghana to suggest daily consumption of hibiscus tea, in a concentrated bioenergized form, lowers blood pressure level and may prove an effective component in cardiovascular health management.
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Integrative Medicine is becoming friendlier and patient centered in clinical science. The author of this paper discusses the integrative approach of allopathic medication and the combination of African herbal formulation for cardiovascular Health for hypertensive crisis. The combination of both protocols helped reduced high blood pressure reading of systolic 203 mmHg and Diastolic of 130 mm Hg to 131 mmHg and 86 mmHg respectively within 24 hour of administration.
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Aim: Women’s health is paramount, yet, is one area under-researched and explored in phytomedicinal industry in Africa. Phyto-gynecology is under-researched and explored in the Ghanaian Traditional Medicine Industry. This paper discusses the development of phytomedicinal product; Women’s formula, approved by the FDA in Ghana for gynecological health. Method: The Product, Women’s Formula Tea produced by RNG Medicine Research Lab, Ghana, West Africa was given to 200 women aged 20-60years for wellness. The patients, distributors or the individual who purchased the product to their loved ones further called or WhatsApp their experiences on the products to the author of this paper. Result: out of the 200 Women who used Women’s Formula for their wellness, 50 reported that, the product had significant impact on sound sleep, 30 also reported urinary health support, 50 further reported increased in their libido, 50 reported improvement on their menstrual health and 20 reported better menopausal symptom management. Conclusion: Each individual has her own opinion on the product and no conclusive specific condition product targets. The product exhibits different mechanism of action in different individual
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Aim: The field of urology is not limited to mainstream medicine and pharmaceutical drugs. Today, Naturopathic doctors, researchers, scientists and even some mainstream doctors are researching into natural remedies to help their patients. Phytomedicinal products are used in our daily lives for prostatic health. However, it is not without controversies. Obviously, controversy about phytomedicinal efficacy continues due to product inconsistency, different trial designs, placebo effects and other factors that make it difficult to assess reasonable trials of different products. This current paper discusses the anecdotal evidences and safety of the development of FDA certified Men’s Formula as phytomedicine for prostate health and immune booster for men with advanced prostate conditions.Method: In the first stage, Six(6) samples of Men’s Formula Tea were sent to the department of Pharmaceutics and Pharmacognosy to assess the microbial loads and phytochemical and physiochemical analysis at Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ashanti region, Ghana. In the second stage, The Product, Men’s Formula Tea produced by RNG Medicine Research Lab, Ghana, West Africa was given to 100 men for either their prostate problem or to boost their sex life. The patients, distributors or the individual who purchased the product to their loved ones further called or WhatsApp their experiences on the products to the author of this paper. Result: out of the 100 Men who used Men’s Formula for their prostate health, 99 reported significant quality of life improvement. They also reported drastic changes in their sexual life. The author also noticed divergent views on health improvements in the patients. One been blood pressure stabilization in dialysis patient for over four years. Conclusion: Anecdotal evidence from patients revealed significant impact of Men’s Formula on their prostate and sexual life. Various mechanism of actions were also discovered which could be
ABSTRACT
Pilocarpus microphyllus (Stapf), is considered the most common species used in medicine and a source of naturally occurring pilocarpine alkaloid. Pilocarpine was first drug introduced in ophthalmology for the treatment of various glaucomatous disorders, but now is consider as third line treatment. Pilocarpine alkaloid found its way in the treatment of xerostomia, regardless of the etiology