Review Article
Genetics of Hydrocephalus (HC)
Irum Naureen, Aisha Saleem, Maham Ghafoor, Farwa Muhammad Ali, Naveed Murad, Zainab Khalid, Muhammad Adnan, Waqas Ahmad
East African Scholars Multidiscip Bull; 2022, 5(9): 176-184
DOI: 10.36349/easjmb.2022.v05i09.001
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ABSTRACT
Genetic hydrocephalus is a neurological condition in which the cerebrospinal fluid (CSF) flows with subsequent and it results in enlargement of the cerebral ventricular cavities. The common cause of the congenital hydrocephalus is the variation in the L1CAM gene, and there is the narrow passage between the third and fourth ventricles. It is suggesting that hydrocephalus is more complicated than the simple CSF , and are many factors which are associated with the genetics of hydrocephalus, the major two factors are the i) telomeres proximity ii) and the more content of Adenine and Thymine [A, T] in the human CH as compared to the other nervous disorders. It is also suggesting that genetics of hydrocephalus is a crucial birth defect, and its genetics is still not completely understood, so it is the most important clinical feature. There are about 43 mutant loci associated with the animals and human hydrocephalus. Among them 9 are associated with animal models and 1 with the human. The most important hydrocephalus gene products are the growth factors, cytokines and many cellular signal pathways in the starting stage of brain development. In this study we will aim to understand the abnormalities in brain cause by the abnormal cellular functioning, and all these cellular events results congenital hydrocephalus. All these studies show that it is the mandolin type of disease with reference to the cellular, molecular genetics, physiological and pathological studies.
Original Research Article
ABSTRACT
Turbidity poses a big problem in water treatment. One of the processing stages in the water treatment unit is the coagulation/flocculation process to remove turbidity. This study uses coral stone and oyster shell powder as locally available natural coagulants to reduce water turbidity. Coral stone and shell powder have now been widely used as a natural coagulant in reducing Mn, Fe levels. However, using coral stone and shell powder as a natural coagulant is still debated. To determine the effectiveness of using coral stone and shellfish powder as natural coagulants in reducing Mn, Fe, and water turbidity levels using the backwashing method. This research is an experimental study with a pretest and post-test design. The population in this study was all water in community dug wells that were cloudy and contained high levels of Mn, Fe, and a sample of 100 liters was taken for filtering experiments and samples for checking levels of Mn, iron (Fe), and water turbidity. This research was conducted at the Health Polytechnic of the Aceh Ministry of Health from July to November 2021. The water analysis was carried out at the Health Laboratory of the Aceh Environmental Health Department. The laboratory tests were analyzed using the paired t-test and the ANOVA test. The results showed an effect of the treatment of coral stone and clamshells on the decrease in Fe content with a P-value of 0.012 (α < 0.05). Likewise, the Mn content affects the treatment of coral stone and shell powder with a thickness of 40 cm, 30 cm, and 20 cm, which affects the decrease in Mn content with a P-value of 0.001 (α < 0.05). The results showed that Fe levels before entering the shelter had a significant difference with the processing of coral and shell powder with a thickness of 40 cm, 30 cm, and 20 cm. Coral and shells with a thickness of 40 cm, 30 cm, and 20 cm with 15 repetitions can reduce Fe content from 5.2476 ppm to the lowest at 2.4747 ppm. Coral Rock and Shell Powder Effective as a ........
Original Research Article
ABSTRACT
In a context of economic fragility and political crisis from 2002 to 2010, Côte d'Ivoire in general and the Autonomous District of Abidjan in particular constitute a booming market for private security. The objective of this study is to analyse the socio-political logic of the development of private security companies in the Autonomous District of Abidjan. The study uses a dual methodological approach (qualitative and quantitative) with appropriate survey tools, namely a documentary review and semi-directed interviews with a category of actors. This enabled us to arrive at the following results: On the one hand, the activities of security companies and their active roles contribute to the maintenance of social and political order. On the other hand, private security organisations fulfil dual functions. That is, a function of social security partners and a function of social security capital of political actors in the reproduction and maintenance of political power.
Original Research Article
ABSTRACT
Women's access to land ownership in Côte d'Ivoire remains a challenge despite a multitude of legal and institutional arsenal favouring their access to land ownership. Moreover, Article 12 of the Ivorian Constitution reaffirms equal access to property for women and men. However, it is clear that the above-mentioned difficulties persist. What are the explanatory elements of land insecurity in rural areas for women? The legal and institutional elements alone are not sufficient to understand this work. Beyond the usual explanatory factors, a reading based on intersectionality allows for an in-depth analysis. In fact, this work first highlights the modes of land tenure and their recompositions, the modes of access and their recompositions, and the organisation of society structures access to land and agrarian practices. Since these elements alone are not sufficient to explain the existence of structural gaps and inequalities of access between women, the theory of intersectionality through the concepts of ethnicity, gender and class (social position and social capital that engenders mobilisable economic, social and political resources). The content analysis enabled the categorisation of women and highlighted the positionalities that facilitate or hinder their access to land ownership. In the end, this study showed that there are inequalities between women in access to land ownership insofar as those with low social capital cannot benefit from full access to their land rights, which confirms our central hypothesis that women's access to land ownership is a function of patrilineal and matrilineal societies and modes of land tenure and their recomposition, associated with the intersection of women's economic, social and political resources in Côte d'Ivoire.
Original Research Article
ABSTRACT
Background: Maintaining one's professional competence in today's quickly evolving environment is essential, and it is crucial that nurses at all levels of the healthcare system demonstrate an interest in continuing professional education that lasts a nurse's whole career. Purpose: The purpose of this study was to determine factors motivating nurses’ participation in continuous professional development in Kenya. Methodology: A cross sectional descriptive study was conducted in Narok County Referral hospital. A mixed method approach, which provided for triangulation that sought convergence and corroboration of the results from questionnaire, was adopted. Purposive sampling was used to recruit 40 respondents for the study. Data was checked for completeness and consistency and then entered into SPSS version 26.0 for analysis. Descriptive statistics used included frequencies, percentage, mean and standard deviation. Findings: Results of the mean and standard deviation revealed that majority of the respondents agreed that career development prospect had motivated them to participate in continuous professional development (M =4.15, SD =0.802). Similarly, the respondents were of the view that they participated in continuous professional development in order to keep themselves up to date with the constant changes in the nursing profession (M =4.40, SD =0.810). Upgrade skills and knowledge and to increase professionalism was another factor that motivated nurses to participate in continuous professional development as depicted by the mean and standard deviation (M = 4.30, SD = 0.939). Conclusion: Due to the complexity of the health care system, nurses are required to remain relevant in their area of practice. Continuous professional development equips the nurse with knowledge and skills to perform nursing care professionally. The critical component in achieving favorable results for quality patient’s nursing care is achieved by lifelong learning through continuing professional