ABSTRACT
Introduction: Rhabdomyosarcoma is the most common soft tissue sarcoma in patients under 25 years of age. The occurrence of mandibular rhabdomyosarcoma in a pregnant woman is rare with an incidence of 0.07 to 0.1 and the literature describes one case per 1000 deliveries. Only biopsy and histological examination make a definitive diagnosis. Treatment is based on a combination of chemoradiation and surgery. Objectives: To describe the diagnostic and therapeutic aspects of mandibular rhabdomyosarcoma in pregnant women. Observation: It was a 19-year-old patient who had consulted for left mandibular swelling evolving over 28 weeks. A morphological assessment had been requested but being almost full-term, the patient chose to let her pregnancy progress. She was seen again after delivery with a swelling that had tripled in volume with abundant bleeding on the alteration of the general condition. The imaging concluded that there was a large osteolytic mass of the mandible. The biopsy performed came back in favor of an infiltrating pleomorphic rhabdomyosarcoma. Treatment consisted of radiation therapy followed by surgery. The evolution was marked by the death of the patient after 01 month of radiotherapy. Conclusion: Rhabdomyosarcoma is an aggressive malignant tumor that most often affects subjects under 25 years of age and its appearance in pregnant women is rare.

ABSTRACT
Introduction: Sickle cell disease is one of the most common genetic haemoglobinopathies. It is a major public health problem and kidney insufficiency is common among adult patients with the disease. The sickle haemoglobin leads to tissue hypoxia, causing acute tissue damage and chronic organ dysfunction including chronic kidney disease. Aim: To assess the prevalence and pattern of kidney disease among sickle cell patients in UMTH, Maiduguri, Borno State. Method: A hospital-based cross-sectional study conducted from January 2022 to June 2022 at the GOP and haematology clinics of the University of Maiduguri Teaching Hospital. Two hundred and forty (240) SCA participants receiving medical care at the outpatient sickle cell clinic were enrolled in the study. An equal number of age and sex-matched controls with Hb AA were also recruited. A structured questionnaire was administered to obtain demographic information, clinical history, blood pressure, and anthropometry. Blood and urine samples were taken for serumcreatinine and proteinuria determination respectively. The estimated GFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Data was analysed using International Business Machines-Statistical Package for Social Sciences (IBM-SPSS) version 21. P –value of < 0.05 was taken as significant. Results: Kidney disease was present in 44.6% of participants with SCA and present in 15% of the controls. The prevalence of hyperfiltration (GFR >120ml/min) and reduced GFR <60ml/min were also significantly higher in the SCA compared with controls 17.5% vs 1.7% and 38.3% vs 12% respectively. (p-value < 0.001). Serum creatinine levels correlated positively with albuminuria (r = 0.178; p = 0.006), while PCV correlated negatively with albuminuria (r = -0.178; p=0.006). The significant predictors of kidney dysfunction were the presence of albuminuria and high diastolic BP, with odd ratio (confidence interval) ...............

ABSTRACT
Aim: To determine the place of abdominal wounds among abdominal traumas and to describe their clinical, therapeutic and evolutionary aspects. Patients and Methods: This was a retrospective descriptive study based on analysis of the records of patients seen for abdominal stab wounds in the general surgery department of the N'Zérékoré regional hospital during the period from January 2011 to December 31, 2020. Epidemiological, clinical, therapeutic and evolutionary parameters were studied. Results: Out of a total of 745 cases of abdominal trauma, we found 89 cases of abdominal stab wounds, a frequency of 12.49%. The average age was 36, with a clear male predominance (78%). Pupils/students were the most represented (32.58%), and criminal assault was the most common circumstance (70.79%). Operative treatment was the most common (74%), and the small intestine was the organ most affected (34.84%); the after-effects were simple in 89.39% of patients, and we recorded 4 deaths (6.06%). Conclusion: Stab wounds of the abdomen are a real public health problem in Africa, especially in low-resource countries such as ours. Surgery is still indicated for severe injuries or complications.