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Background: Hemorrhoids are anal cushions that enlarge, bleed, thrombose, prolapse, and result in clinical complaints. Surgery is the recommended course of action for people with grade III or grade IV haemorrhoids. The purpose of this study was to evaluate the clinical characteristics, operating time, hospital stay, and postoperative complications of the two haemorrhoid surgery procedures: open hemorrhoidectomy and stapled haemorrhoidopexy. Methods: A retrospective cross-sectional study was carried out at the department of Surgery in Kumuduni Women's Medical College, Tangail from January 2020 to January 2021. The current study covered all 84 patients, 42 of which underwent open surgery and 42 of which underwent stapled treatment. Version 20 of SPSS was used for the statistical analysis. In order to compare the results between the groups, both parametric and non-parametric tests were performed. Result: The mean age of patients was 39.05±5.29 years for the stapled haemorrhoidopexy group and 39.52±5.22 years for the open hemorrhoidectomy group. Most 23(54.8%) participants were male and 19(45.2%) were female in the stapled group whereas 25(59.5%) were male and 17(40.5%) were female in the open hemorrhoidectomy group. The stapled haemorrhoidopexy group's mean ± SD of intraoperative bleeding was 48.44±.9.42 ml, the average hospital stay was 1.42±.94 days and the average surgical duration was 1.42±.94 minutes. The mean ± SD of intraoperative blood loss for the open hemorrhoidectomy group was 72.65±11.92 ml, the mean hospital stay was 3.3±2.9 days, and the mean operational time and standard deviation were 49.12 ± 6.46 minutes. It was discovered that the open group had a higher rate of urine retention. Six (14.3%) patients in the stapled group experienced post-operative bleeding, compared to nine (21.4%) in the open group. In addition to 31% of patients in the stapled group, 57.1% of patients in the open group reported pain. Conclusion: In conclusion, this study reveals ....

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Objective: The purpose of the study was to determine the clinical pattern of Herpes Simplex Virus (HSV) Keratitis and to evaluate the precipitating factors and associated visual loss. Materials and Methods: This was a retrospective study of all consecutive patients clinically diagnosed with HSV keratitis in the Cornea department of Rapti eye hospital from January 2022 to December 2022. The major outcome measures studied were demographic characteristics, clinical pattern of HSV keratitis, precipitating factors and visual acuity. Result: A total of 218 cases of HSV keratitis were included in the study. Mean age of patients was 39.23±20.19 years with majority belonging to age group 15-40 years. Stromal keratitis was the most common manifestation (109 cases; 50%) followed by disciform keratitis. Majority of cases had spontaneous onset and others had precipitating factors like minor ocular trauma, steroid and fever. Presenting visual acuity of <3/60 was present in 14.2% of cases. Conclusion: Productive age group are most commonly affected with HSV keratitis with stromal keratitis as the most common presentation. HSV keratitis may lead to significant scarring and severe visual impairment and blindness.

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Introduction: PCOS is a common condition in women of reproductive age characterized by ovulatory dysfunction, androgen excess and polycystic ovaries. Myoinositol and metformin have both been studied as potential treatment options for inducing ovulation in women with PCOS. Aim of the Study: The aim of the study was to compare the use of myoinositol and metformin for ovulation induction in pregnant women with PCOS. Methods: This comparative observational cross-sectional study was conducted at the Manikganj 250 Bedded Sadar hospital, Dhaka, Bangladesh from January 2022 to December 2022. A total of 100 patients with PCOS were selected for this study. The participants were divided into 2 equal groups of 50 patients each, where patients in the first group were treated with myoinositol, and patients in the second group were treated with metformin. Result: In our study, there was a decrease in mean weight, BMI, and waist-hip ratio of both groups after treatment but with no statistically significant (p>0.05) difference between the groups. There was an improvement in menstrual cycle in both groups after treatment with no statistically significant (p>0.05) difference between the groups. The LH/FSH ratio decreased more in the myoinositol group after treatment compared to the metformin group but there was no statistically significant (p>0.05) difference between the groups. Fasting Insulin decreased similarly in both groups but there was no statistically significant (p>0.05) difference between the groups. HOMA-IR decreased in both groups with a statistically significant (p<0.05) difference after treatment. We found that myo-inositol administration in PCOS subjects led to statistically significant (p<0.05) decreases in FAI compared to the metformin group. Ovarian volume decreased from 12.59±5.15 cm3 to 10.05±4.50 cm3 in the myoinositol group and 12.90±5.62 cm3 to 10.65±4.10 cm3 in metformin group. The groups had no statistically significant (p>0.05) difference. The conception ....

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Background: Neonatal sepsis or septicemia is the term that has been used to describe the systemic response to infection in a newborn infant during the first 28 days of life. Neonatal mortality is increasingly recognized as an important global public health challenge that must be addressed if we wish to reduce child death disparities between rich and poor countries. Most of the estimated 4 million neonatal deaths per year occur in low and middle-income countries. Objective: The aim of this study is to evaluate the role of C-reactive protein (CRP) in the diagnosis of neonatal sepsis. Method of the Study: This is a cross-sectional study carried out in the Department of Neonatology, BSMMU, Dhaka over a period of 6 months between January 2013 to June 2013. Newborns with suspected sepsis admitted to BSMMU were the study population. Clinically diagnosed cases of neonatal sepsis aged < 28 days of both sexes whose parents or guardians provided informed consent were eligible for enrollment in the study. The subjects were selected consecutively from the study population. Data were collected using a structured questionnaire containing all the variables of interest. Data were processed and analyzed using the computer software SPSS (Statistical Package for Social Sciences). The test statistics used to analyze the data were Chi-square (χ2) or Fisher’s Exact Probability Test & Student’s t-Test. Result: The sensitivity of CRP in correctly detecting neonatal sepsis of those who have the disease is 94.44%, while the specificity of the test in correctly differentiating neonates who do not have the disease is 13.72%. The positive predictive value (PPV) of the test is 27.86% and the negative predictive value of the test is 87.5%. The percentages of false positives and false negatives as yielded by the test are 72.13% and 12.5% respectively. Conclusion: The sensitivity of CRP was higher at 94.44% but specificity was low 13.72%. A combination of tests may increase the sensitivity, ........

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Introduction: Hypospadias is a congenital defect that affects the development of the urethra in males, causing the urethral opening to be located on the underside of the penis rather than at the tip. Repair of hypospadias is a surgical procedure that aims to create a normal-appearing and functional penis that allows for normal urination. The tubularized incised-plate (TIP) technique is a widely used surgical approach for correcting distal hypospadias. TIP urethroplasty can be performed using either continuous or interrupted suture techniques. The present study aims to compare the complications of these two techniques in TIP urethroplasty for the repair of hypospadias. Aim of the Study: The aim of the study was to compare the complication rate among continuous and interrupted suture in TIP urethroplasty for anterior hypospadias repair. Methods: This Prospective Randomized comparative study was conducted at the Department of Pediatric Surgery, Bangladesh Shishu Hospital & Institute, Dhaka, Bangladesh. The study duration was 5 years, from July 2017 to June 2022. After some drop-out patients, a total of 68 patients had been left, with Group-1 having 35 continuous suture TIP urethroplasty, and Group-2 having 33 interrupted sutures TIP urethroplasty. Result: The mean age of participants was 41.15±24.46 months in Group-1 and 38.05±25.14 months in Group-2. The mean weight of participants was 17.79±6.37 kg and 19.14±9.19 kg in Group-1 and Group-2 respectively. Operation time in group 1 and group 2 was 66.86±3.51 minutes and 79.38±5.04 minutes respectively, with statistically significant difference. But none of the post-operative complications had significant difference between the groups. Conclusion: The study showed that although operative time was significantly lower among patients undergoing continuous suture for TIP urethroplasty instead of interrupted suture TIP urethroplasty, the overall complications rate had no significant difference between the groups.

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Introduction: DDH is the most common congenital anomaly of the musculoskeletal system in newborns. The disease ranges from a simple flattening of the acetabular cavity to the complete dislocation of the femoral head. Most developed countries report an incidence of 1.5 to 20 cases of DDH per 1000 births, depending in part on the methods of screening used. It includes a wide spectrum of hip alterations: neonatal instability; acetabular dysplasia; hip subluxation; and true dislocation of the hip. Aim of the Study: The aim of this study was to evaluate the management of the Developmental Dysplasia of Hip (DDH) in children. Methods: This retrospective study was conducted in the Department of Pediatric Surgery, Bangladesh Shishu Hospital & Institute, Dhaka, Bangladesh during the period from January2018 to December 2021. Result: In total 54 neonates completed the study. In our study we found majority (53.70%) of children were aged less than 4 months old. Followed by 25.93% & 20.37% were aged 1-2 months & 3-4 months respectively. Majority of neonates were girls (61.11%) compared to boys (38.89%). The highest risk factors of DDH was breech presentation (19%).We found that majority of neonates (70.37%) had dysplasia on left side and 7.41% had dysplasia on right side respectively. The prevalence of bilateral condition was 12(22.22%). Conclusion: DDH a common congenital anomaly that can be successfully treated non-operatively if detected early. For older individuals with dislocated or unstable hips, surgery is necessary. Surgery's function in treating acetabular dysplasia in children is changing and largely determined by symptoms. Expanding therapy choices for DDH and improved anatomical patient assessment skills among doctors will result in the proper intervention at the right time.

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Neurofibromatosis type I (NF1) or Von Recklinghausen disease is one of the most frequent genetic diseases with polyvascular manifestations, including the eye. Its prevalence was variously estimated varying between 1/7800 and 1/2000. The diagnosis of NF1 is essentially clinical based on criteria established by the consensus conference of the National Institute of Health (NIH) in 1988. Several complications have been reported by numerous authors in cases of plexiform neurofibromas sometimes associated with congenital glaucoma. We report two cases of monocular blindness, complications of this disease in children, responsible for stigmatization by their peers and school dropout, seen at the National Hospital of Zinder, Niger.