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Original Research Article
ABSTRACT
Fungus isolates were obtained from the roots and leaves of the infected broad bean from Hawija district of Kirkuk city and isolated on the medium of PDA by examining its morphological and phenotypic characteristics of the fungus and the shape of conidia. In this study, 16 male rabbits were brought from the local markets of the city of Kirkuk and divided into 4 groups, each group consisting of 4 rabbits, the first group includes a control group, the second group is an infected group, the third group is an infected group that was treated with 50 mg of plant leaf extract, and an infected group was treated with 100 mg of leaf extract, after which Oxidative stress factors levels were checked. Oxidative stress factors showed high levels of MDA in infected rabbits compared to normal rabbits (P < 0.05), while GSH and catalase levels appeared lower compared to MDA in infected rabbits (P < 0.05), while in the group of rabbits treated with leaf extract 50 mg and 100 mg) showed few changes in concentrations MDA, GSH and Catalase compared to normal rabbits (P < 0.05).
Original Research Article
ABSTRACT
In emergency medicine, Troponin Ic is a useful diagnostic and prognostic biomarker in the management of ischemic cardiac pathologies. However, its prescription often exceeds international recommendations. The aim of this study is to evaluate practices concerning the prescription of Troponin assays in the emergency department of the Mohammed V Military Training Hospital in Rabat. This is a prospective study. Was included in this study, every patient admitted to the emergency department of the Mohammed V Military Training Hospital in Rabat and having at least one troponin assay during the period from December 25, 2020 to January 12, 2021. The assay was performed using the "ARCHITECT STAT Highly sensitive troponin-I" method. 135 patients for whom have prescribed a Troponin assay during the period of study. A total of 219 assays were performed. The mean age was 64 years, with a predominance of males. The main reasons for admission were chest pain (29.6%), dyspnea (26.6%), neurological disorders (16.3%) and respiratory distress (10.3%). A high Troponin Ic value during the first determination was observed in almost 37% of cases. In 63% of cases, the value was negative. 53.3% of prescriptions were considered as irrelevant according to pre-established criteria. A repeated Troponin Ic assays were performed in 31% (n=127) of cases. They were deemed relevant in 25% of cases. In 6% of patients, the appropriateness of repeat assays was not demonstrated. Compliance with good prescribing practices for Troponin significantly reduces the number of unjustified samples, with a real economic impact.
Original Research Article
The Seroprevalence of Parvovirus B19 at the Laboratory of Virology of IBN Sina Rabat University Hospital
Hind Zahid, Amal Zouaki, Sophia Tazi, Ghizlane el Amin, Jalila Zirar, Nora Touyar, Leila Laamara, Myriam Seffar, Hakima Kabbaj
Cross Current Int J Med Biosci, 2024; 6(2): 33-37
DOI: 10.36344/ccijmb.2024.v06i02.001
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88 Downloads | March 4, 2024
ABSTRACT
Parvovirus B19 (PVB19) is a DNA virus whose main tropism is erythroid precursors, it is responsible for infections that can be life-threatening in fetuses and immunocompromised individuals. The aim of this study was to determine the seroprevalence of Parvovirus B19 in a Moroccan population. We conducted a retrospective study between March 2019 and July 2022 at the Central Laboratory of Virology of Ibn Sina University Hospital of Rabat. All included samples were qualitatively tested for parvovirus B19 anti-VP2 IgG by ELISA on the Chorus analyzer (Diesse diagnostic). Of the 343 patients included, 181 (53%) were women. 165 (48%) were adults with an average age of 45 years [17 - 89], while 178 (52%) were children with an average age of 6 years [0.7 - 16]. Anti-PVB19 IgG were positive in 166 patients, giving an overall seroprevalence of 48.4%. The latter was significantly higher in adults (63.1% vs. 34.8%; p= <0.001) and increased significantly with age, from 32.5% in children aged [7 months to 5 years], to 65.1% in patients over 35 years (p= <0.001). Gender had no impact on seroprevalence. Our study showed an overall seroprevalence of parvovirus B19 of 48.4%. Seroprevalence increased significantly with age, which aligns with the findings in the literature. No previous data in Morocco.
Original Research Article
Knowledge and Practice of Vector Control against Malaria by Mothers of Children Aged 06 to 59 Months Hospitalized for Severe Malaria in the Pediatric Department of the Reference Health Center of Commune I of Bamako
Ouazoun Coulibaly, Daouda Camara, Yacouba Sylla, Fatoumata Diakite, Amadou Landouré, Bakary Keita, Chaka Keita, Kadiatou Ba, Belco Maiga, Oumar Coulibaly, Diakaridia Kone, Nouhoum Traore, Ousmane Diam
Cross Current Int J Med Biosci, 2024; 6(1): 26-32
DOI: 10.36344/ccijmb.2024.v06i01.006
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94 Downloads | Feb. 14, 2024
ABSTRACT
Introduction: Severe malaria is a public health problem that causes a real socio-economic burden in developing countries. It is associated with high but avoidable mortality thanks to preventive and curative measures. Methodology: This is a descriptive and cross-sectional study with a prospective survey for the benefit of mothers of children aged 06 to 59 months hospitalized for serious malaria in the pediatric department of the Reference Health Center of Commune I of Bamako from October 2021 to September 2022. Results: In 12 months, 624 children were hospitalized, including 151 children aged 6 to 59 months suffering from severe malaria. The hospital frequency of severe malaria in this age group from 06 to 59 months was 24.2%. The average age of the mothers interviewed was 27.8 years with a range of 15 to 48 years. Mothers were educated in 84.1%, married in 98.7% and working as housewives in 81.5%. The reason for consulting children was fever (91.4%), anorexia (90.1%), prostration (79.5%). Mothers knew about impregnated mosquito nets and smoke coils as means of prevention against malaria at the same frequency of 99.3%, repellent creams 96.7%, and indoor spraying in 92.7%. In practice, they used smoke coils in 64.2%, repellent cream in 44.4% and mosquito nets impregnated with insecticide in 40.4%. Mothers attributed the cause of malaria to mosquito bites in 91.4%; They had readjusted the way sick children were fed by giving more food than usual (29.8%), splitting meals (21.8%) or using active feeding (14.6%). Most children had severe malaria, neurological form or anemic form at the same proportion of 37.1%. The assessment of the nutritional status of children revealed 18.5% acute malnutrition. The children had received conventional and traditional self-medication in 63.58 and 58.94% of cases respectively before admission. In children, a significant relationship was noted between severe anemic malaria and acute malnutrition (Fisher's exact test = 18.41; p = 0.01). ....
Original Research Article
ABSTRACT
Sexual and haematological abnormalities are on the increase, hence the need to identify possible ameliorative agents. The present study evaluates the effects of the hydromethanol leaf extract of Craterispermum schweinfurthi on sperm characteristics and haematological indices in male wistar rats. A total of 20 male wistar rats weighing between 100-250g were randomly divided into 4 groups of 5 rats each and treated as follows for 28days: Group A: Negative control: Group B, C and D received 250mg/kgbw, 500mg/kg bw and 750mg/kg bw of extract. On day 29, the rats were placed under chloroform anaesthesia and blood samples collected for the estimation of serum total white blood cell, red blood cell and platelet counts. Also, rats caudal epididymides were isolated for sperm characteristics estimation. Compared to Group A rats, significantly higher values of sperm count, active sperm, and population of normal sperm were observed amongst Groups B-D rats in a dose dependent manner (p<0.05). For sperm volume and viability, significant increases were observed amongst Group D rats only compared to Group A rats (p<0.05): Suggesting a possible greater potency of the extract at 750mg/kg body weight. Population of abnormal sperm, sluggish sperm and dead sperm were significantly decreased amongst Groups B-D rats compared to Group A rats (p<0.05). Similarly, a significant and dose dependent increase in total WBC, RBC and PLT counts following graded extract doses administration were observed amongst rats in B, C and D Groups compared to Group A rats: Demonstrating a possible blood boosting potentials of the extract in male wistar rats. The extract apparently exhibits potential beneficial effects on sperm characteristics and haematopoiesis in male wistar rats.
Original Research Article
ABSTRACT
Depression is a multifactorial disease that globally impacts all ages and sectors of the population. In this sense, it has become a public health problem, since it affects 280 million people in the world, according to information from the World Health Organization. Older adults represent 5.7% of the population that experiences this disease, with the moderate to severe stage being the one that most impacts their health, and, therefore, quality of life. For this reason, the objective of the research is to know the prevalence and psychosocial risk factors associated with depression in older people in the community of Santa Cruz, Hecelchakán, Campeche. The methodology used is with a quantitative approach because information was collected, based on the application of the Yesavage scale of geriatric depression, and the sociodemographic registry of 60 older adults of both sexes, in order to measure the percentage of prevalence through its respective epidemiological formula. Likewise, it is cross-sectional because it collected data in a single time: November 2022 – October 2023. Results: 46.7% experienced mild depression, 41.7% moderate depression and 11.6% severe depression. 55% of those interviewed were male and 45% female. The actual prevalence of depression is 100%. Likewise, the psychosocial risk factors identified were: the absence of recreational activities and social support networks, the economy, health services and family disintegration. Finally, it is necessary to design and implement socio-health intervention projects in the locality and with a socio-cultural perspective that impacts this age group, the family and from an intergenerational perspective, with the promotion of mental health being a priority goal in their execution.
ABSTRACT
Balanitis is the inflammation of the glans penis while balanoposthitis involves both the glans penis and prepuce and occurs only in uncircumcised males. Balanitis is more common in uncircumcised males due to the occlusive effect of the foreskin, which facilitates smegma retention and bacterial and fungal overgrowth. Therefore, balanitis is rare after circumcision and severe balanitis is even rarer. In patients with recurrent balanoposthitis, circumcision is indicated, and the presence of diabetes should be ruled out. Diabetes mellitus is a frequent predisposing factor for Candida balanoposthitis and has been associated with male genital lichen sclerosus, which in progressive stages leads to phimosis. Circumcision is also indicated in the treatment of lichen sclerosus associated with phimosis. Candida albicans stands as the primary culprit in cases of acute infectious balanoposthitis, with aerobic bacteria constituting the second most common etiological factor. Among these bacteria, streptococci particularly groups B and D and staphylococci, notably S. aureus, are prevalent. Mixed infections may also occur. The typical clinical manifestations involve erythema and oedema accompanied by itching and/or pain. In instances of painful, erosive streptococcal balanoposthitis, severe balanopreputial oedema with purulent exudate can be observed. Staphylococcus haemolyticus, a prominent member of the coagulase-negative staphylococci of the skin microbiota, causes infections in the male urogenital tract, such as urinary tract infections, chronic prostatitis and epididymo-orchitis. However, it had not been associated with balanitis. Enterococcus faecalis is part of the normal gastrointestinal microflora and is also a frequent cause of urinary tract infections and of chronic prostatitis. Enterococcus has been associated with mild balanoposthitis in adults and E. faecalis has been described to cause balanoposthitis in young children, but its association with severe balanitis .....